The Fight Night card will take place at the Nilson Nelson gymnasium in Brasilia, Brazil, and air live on ESPN+.
Walker (17-4) suffered his first setback in the Octagon in November, losing by first-round knockout to Corey Anderson at UFC 244. Prior to that, the rising 205-pound sensation scored quick finishes against Misha Cirkunov, Justin Ledet and Khalil Rountree.
Krylov (27-6) is also looking to get back to the winning column after losing a thrilling bout to Glover Teixeira in September, the first decision defeat of his career. The Ukrainian talent is 1-2 since returning to the Octagon in 2018, submitting Ovince Saint Preux following a loss to Jan Błachowicz.
Silva (6-0) submitted Gillian Robertson with an armbar with five seconds left in the clock in the opening round in her debut in Sept. 2018, but suffered a serious knee injury during the bout and has since been sidelined.