Darren Till is headlining at home again.
Fresh off a second-round submission loss to welterweight champion Tyron Woodley, Till will be looking to avoid the first losing streak of his career when he takes on Masvidal, a veteran of 45 fights.
Meanwhile, Edwards could increase his win streak to seven with a win over Nelson, who has won three of his last four.
UFC Fight Night 147 takes place at The O2 Arena in London on March 16 and the main card will air on the ESPN+ streaming service.
See the updated card below (bout order to be determined):
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