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Matt Brown injured, out of TUF Latin America 2 Finale headliner against Kelvin Gastelum

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Esther Lin, MMA Fighting

The UFC's fourth-quarter slate just lost another main event. Welterweight contender Matt Brown has been forced to withdraw from his Nov. 21 headlining fight at the finale of 'The Ultimate Fighter: Latin America 2' against Kelvin Gastelum after suffering an ankle injury in training.

The UFC confirmed the news to MMAFighting.com on Monday following an initial report by FOX Sports. A search for a replacement is currently underway, with the hopes of keeping Gastelum on the card.

Gastelum (11-1), a former 'TUF 17' winner, served as head coach on 'TUF: Latin America 2' this season alongside Efrain Escudero.

The 24-year-old was scheduled to make his return to the welterweight division after defeating Nate Marquardt in a brief and successful trip to middleweight. Gastelum holds past victories at welterweight over the likes of Jake Ellenberger and Rick Story, along with a split decision win at 185 pounds over Uriah Hall.

According to FOX Sports, while Brown's injury isn't severe, it was bad enough that the top welterweight contender "had no choice but to pull out" with the fight just weeks away.

TUF Latin America 2 Finale will take place at Monterrey Arena in Monterrey, Mexico and air live on FOX Sports 1. An updated fight card can be found below.