Gringo Super Fight announced Tuesday that "Cyborg" and Manhoef are set to collide one more time on April 13 in Rio de Janeiro, Brazil, for the vacant welterweight championship. In the first fight, Manhoef stopped the Brazilian with punches in the second round.
Manhoef (27-11-1, 1 no-contest), who is set to make his 170-pound debut, went 15-9 (and one no-contest) since that battle with "Cyborg" in London, scoring wins over Kazushi Sakuraba, Mark Hunt, Kazuo Misaki, and Denis Kang.
Santos (19-15) competed at Pride, Sengoku and Strikeforce since losing to Manhoef. "Cyborg" has fought top competition in Gegard Mousasi, Nick Diaz and Siyar Bahadurzada in those promotions, defeating the likes of Francis Carmont and Marius Zaromskis in his 7-7 run since 2006.