Pudzianowski took to the scale first and weighed in at 273 pounds, 10 pounds less than his KSW fight held in Poland just two weeks ago. He has reportedly spent much of the time since working on his conditioning.
The 6-foot-8 Sylvia checked in at 305 pounds, 18 pounds heavier than he weighed in his last fight held eight months ago.
The Sylvia-Pudzianowski fight will be contested in the super-heavyweight division.
The co-main event is heavyweight matchup featuring Travis Wiuff against Josh Barnes. Wiuff weighed 253, nine pounds lighter than Barnes.
The card emanates from the DCU Center in Worcester, Mass. at 9 pm on Friday.
Moosin: God of Martial Arts weigh-in results
Tim Sylvia (305 lbs.) vs. Mariusz Pudzianowski (273 lbs.)
Travis Wiuff (253) vs. Josh Barnes (262)
Travis Lutter (185) vs. Rafael Natal (185)
Yves Edwards (157) vs. Mike Campbell (156)
Tara LaRosa (129) vs. Roxanne Modafferi (128)
Ho Jin Kim (196) vs. Lukasz Jurkowski (214)
Ralph Johnson (171) vs. Forrest Petz (170.5)
Matt Lee (170.5 vs. Brett Oteri (175.5)
Fred Belleton (185) vs. Anthony Lapsley (185)
Paul Barry (245) vs. Stipe Miocic (241)